Category Archives: Publications

Health Commons: Therapy Development in a Networked World by Marty Tenenbaum and John Wilbanks

Drug Discovery: Time for a Change The pharmaceutical industry is at a crossroads. Despite revolutionary advances in molecular biology that have made genetic decoding routine, the time from gene to cure still stands at 17 years. High-throughput screening methods allow us to test the efficacy of millions of compounds against a molecular target in a […]

PLoS ONE: Targeted Therapy Database (and Analyzer)

Online Tools for Personalized Cancer Therapeutics Analysis We created a manually annotated database (Targeted Therapy Database, TTD) where the relevant data are gathered in a formal representation that can be computationally analyzed. Dedicated algorithms were set up for the identification of the prevalent therapeutic hypotheses based on the available evidence and for ranking treatments based […]

PLoS ONE: A Melanoma Molecular Disease Model

Peer Reviewed Molecular Disease Models While advanced melanoma remains one of the most challenging cancers, recent developments in our understanding of the molecular drivers of this disease have uncovered exciting opportunities to guide personalized therapeutic decisions. Genetic analyses of melanoma have uncovered several key molecular pathways that are involved in disease onset and progression, as well as prognosis. […]

CollabRx Scientists Jeff Shrager, Marty Tenenbaum, and Mike Travers Describe Cancer Commons in “Collaborative Computational Technologies for Biomedical Research”

Methods, Processes, and Tools for Collaboration “The time has come to fundamentally rethink how we handle the building of knowledge in biomedical sciences today. This book describes how the computational sciences have transformed into being a key knowledge broker, able to integrate and operate across divergent data types.”—Bryn Williams-Jones, Associate Research Fellow, Pfizer The pharmaceutical […]

CollabRx Targeted Therapy Finder noted by FDA (Genome Web)

An article appearing in the Nov. 2, 2011 issue of Genome Web highlights the CollabRx Targeted Therapy Finders in the context of a discussion about the complexities of pre-screening regarding clinical trials for personalized (targeted) therapies. Thomas Gwise, deputy director of the FDA’s biometrics division, is quoted as saying that online tools such as the […]

Targeted Therapies Improve Prognosis for Lung Cancer Patients

February, 2012 — CollabRx’s Lung Cancer Targeted Therapy Finder and Dr. Ravi Salga, chief editor and advisor for the Lung Cancer Targeted Therapy Finder, are featured in an article published by the University of Chicago School of Medicine as part of their Comprehensive Cancer Center’s lung cancer program. Read More at University of Chicago  

Lung Cancer Molecular Disease Model Published in PLoS ONE

A team including leading lung cancer researchers, and CollabRx scientists, has just published a novel Lung Cancer Molecular Disease Model in PLoS ONE, a leading peer-reviewed open source journal. (click here to read the published paper online). This is the model that underlies the CollabRx Lung Cancer Targeted Therapy Finder App.    

Cancer Commons Researchers Publish Molecular Disease Model for Lung Cancer

PALO ALTO, Calif.–(BUSINESS WIRE)–Cancer Commons, an open‐science initiative to personalize cancer treatments and accelerate research, announces the publication of a molecular disease model (MDM) for lung cancer. The paper, by Lisandra West, Ravi Salgia, and others will appear in the February 21st issue of PLoS ONE. The lung cancer MDM classifies the disease into subtypes based […]

CollabRx apps discussed in the British Journal of Healthcare Computing

The CollabRx Colorectal Targeted Therapy App, and our relationship with CAP (The College of American Pathologists) is briefly described in the latest issue of the British Journal of Healthcare Computing. The article quotes the chief editor of the app, Dr Heinz-Josef Lenz, professor at the Keck School of Medicine, University of Southern California: “The Therapy Finder […]

CollabRx and Collaborators at Leading Academic Centers Publish Clinical Decision Support Model for Precision Oncology

Publication Establishes Standard Framework to Guide Therapy Selection for Targeted Therapies in Cancer SanFrancisco,CA –November5,2014– CollabRx, Inc. (NASDAQ: CLRX), a leading provider of clinical decision support solutions in oncology, today announced the publication of a clinical decision support model for oncology as an advance publication in the current online edition of the open-access journal Oncoscience.1 The publication […]