Who Owns Patient Data in Clinical Research?

There is a popular belief that there will be faster progress in the research for cancer if there is more participation by the patients. Sharing the date will most certainly help. But takes the credit for owning that data and what responsibilities and rights come from that?

For better medical practices, exchanging of data between the doctors and their patients is of utmost importance – and that data is essential for the medical progress and research.

Doctors, traditionally are collecting all the information for the patient’s health such as the medical history, prescribed drugs, tests from the laboratory, etc., and sometimes they can share that information with their doctor colleagues for additional advice.  So the medical records are the property of the physicians.

A Proposed New FDA Drug Approval Pathway: “Conditional”

The time that is taking from the discovery, then validation through approval and the use of the new treatments for cancer is taking too long. There are a lot of experimental treatments that are promising, and the increasing advances in computer technologies and Biostatistics, are bringing the question for “Conditional Approvals” issued by the FDA.

All the oncology advances were made in the first years when there weren’t any regulations. When there was an idea, the doctors put that idea to work almost immediately by adjusting and combining the treatments until they become standardized treatments. There were a lot of types of cancer cured with these kinds of treatments.

Unfortunately, those patients that have glioblastoma or pancreatic cancers, can’t afford this way of finding the treatment or the approval of new drugs.

Leading Retractions in the Cancer Research Literature

Retraction Watch founded in 2010 has filled and helped to thrive a substantial niche. Cancer literature has presented a lot of important corrections and retractions up to date.

Over the years we have seen a certain number of cases regarding retractions in the cancer research. 

On top of the list most certainly is Anil Potti from Duke University, whose work was focused on oncogenomics – with the use of genetic information to calibrate the chemotherapy has proved to be fake. Potti’s work, however, has triggered numerous lawsuits from Duke’s patients, which are now settled, and retraction on 11 papers, which were co-authored by him.

CollabRx and OncoDNA Partner in Molecular Diagnostics

San Francisco, Calif., April 4, 2013 – CollabRx, Inc. (NASDAQ: CLRX), is a company for data analytics and its main focus is on informing on making clinical decisions in molecular medicine, and OncoDNA, SA, a company from Belgium that is providing DNA NGS tests (next-generation sequencing) for clinical use in the field of cancer, announced their multi-year contract for purchasing CollabRx’s SaaS-based technology and other resources to be used in complementation with OncoDNA’s panels for cancer mutation.

These two companies are developing a medical solution and combined test, by comparing the results from OncoDNA’s panels for cancer mutation with the clinical knowledge from CollabRX.



Vegetables and a Cancer Prevention Diet

Avoid Cancer with Antioxidant Rich Anti-Cancer Vegetables

Veggies have shown powerful anti-cancer properties in the lab. Here’s a guide to the best vegetables to include in a cancer prevention diet.

Scientists say that vegetables can be one of the most important components of a cancer prevention diet and one of the best foods that fight cancer. Here are some of the best vegetables to eat to avoid cancer:

Broccoli and Cauliflower in an Anti-Cancer Diet

Three to four weekly servings of broccoli and cauliflower can protect the body from colon cancer, according to one study. Even a mere single serving each week reduces the risk of prostate, breast and ovarian cancers.

Eating Onions to Stop Cancer in its Tracks

Onions may actually stop cancer cells in their tracks, according to a study by Cornell University scientist Dr. Rui Hai Liu. The strongest flavored varieties, such as Northern Red, Western Yellow, and shallots, appear to have the strongest effect, especially against liver and colon cancer. The phenolic and flavonoid compounds in onions are what gives them this dramatic anti-cancer activity.

Antioxidant Rich Tomatoes and Cancer Prevention

Eating two to ten tomato sauce-based meals each week lowers the risk of certain cancers, including prostate cancer, by 25 to 50%. Studies at Brigham and Women’s Hospital and the Harvard School of Public Health have both shown strong effects of tomatoes on preventing the development and spread of many different types of cancer. Lycopene is the magic ingredient in tomatoes that offers these amazing health benefits.

Reduce Cancer Risk with Cabbage and Sauerkraut

Both fresh cabbage and its pickled cousin sauerkraut contain the compounds glucosinolate and indole-3-carbinol (I3C), among other components, which have been shown to lower breast cancer risk, along with the risk of other types of cancers. Young women in adolescence and young adulthood can especially benefit from the anti-cancer activity of cabbage. Scientists at the University of New Mexico Michigan State University and the National Food and Nutrition Institute of Warsaw, Poland have been studying the anti-cancer properties of cabbage and sauerkraut. The recommended consumption of cabbage and sauerkraut to prevent cancer is three servings a week or more.

Broccoli Sprouts Help Fight Cancer

A diet rich in broccoli sprouts may help prevent stomach and bladder cancer, according to Japanese scientists at the University of Tsukuba. Broccoli sprouts contain sulforaphane and isothiocyanates (ITCs), powerful cancer prevention compounds.

Varying Veggies is Key to Cancer Prevention

Including specific vegetables in a cancer prevention diet is a good idea, but eating a lot of different types of veggies may be even more important. Women who eat four or more servings of various types of vegetables each day have a fifty percent lower risk of developing breast cancer than those who only eat two servings, according to one study. One reason for this may be that components from the different vegetables act together, multiplying the health effects.

There is also some evidence, including a study from the Roswell Park Cancer Institute, that munching on raw veggies may be more beneficial than cooked ones since cooking seems to break down some of the powerful anti-cancer ingredients in vegetables. Nonetheless, for those who prefer their vegetables cooked, eating cooked vegetables is still better at preventing cancer than eating no vegetables at all.


Post-Cancer Skin Care and Sun Protection

Anyone who has suffered from skin cancer needs to take extra special care to avoid getting burnt and always wear high factor sunscreen.


Everyone needs to be careful in the sun, in order to prevent getting sunburn or developing a form of skin cancer. However, those who have previously suffered from skin cancer must do their utmost to be safe in the sun.

Post-Cancer Skin Care – Check Skin Regularly

As those who have previously suffered from skin cancer such as malignant or non-malignant melanoma have a greater risk of it returning, it is important to check the skin regularly for changes. In Skin Cancer and Sun Safety – The Essential Guide, Newcombe (2010) identifies checking skin regularly and seeking medical attention for the following:

  • Spot or sore patch of skin that appears and doesn’t heal within a month
  • Spot or sore area, itches, painful, crusted over or bleeds
  • The skin formed into ulcer for no apparent reason

Moles should also be checked, regardless of whether one has had skin cancer in the past or not. Key signs to look out for, as suggested by Newcombe (2010) include:

  • New mole looking different/unusual
  • Existing mole growing in size
  • Ragged or uneven-edged mole
  • Painful, uncomfortable, itchy mole
  • Varying shades of color in mole
  • Inflamed or red-edge mole
  • Bleeding, oozing or crusty mole

Getting into the habit of checking skin regularly is useful for the whole family to do, with this being the quickest way to pick up on any signs or symptoms that all is not well. This is especially important in the case of malignant melanoma which can be lethal, particularly if not caught and treated in time.

Post-Cancer Sun Protection – Stay Healthy, Avoid Sunburn

Staying safe in the sun requires regularly applying sunscreen, wearing sun protection clothing, sunglasses and following the ABCs of sun protection.

Anyone who is a former sufferer of skin cancer must take extra precautions during warmer days, to avoid the risk of skin cancer returning. It is also very dangerous to use a sunbed, making fake than the safest option available.To take care of skin after cancer, Newcombe (2010) suggests the following sun safety guidelines:

  • Wear close clothing made with weave cotton when out on sunny days
  • Choose trousers and shirts with long sleeves, rather than shorts and vest tops
  • Find a hat offering good protection for the neck and your face
  • Try to stay away from the sun at its strongest, from 11 am until 3 pm
  • Always wear broad-spectrum, high factor sunscreen
  • Wear wraparound sunglasses for better eye protection
  • Never allow the skin to get burnt

As highlighted above, those who have has skin cancer such as malignant melanoma are at a higher risk of cancer returning. Checking moles and skin regularly for any signs or symptoms and always wearing high protection sunscreen is important, as is wearing sunhats, sunglasses and avoiding sunburn.