Future Prostate Cancer Treatments Might Be Guided by Math

Scientists at Ohio State University have designed a first draft of a mathematical model that someday could guide treatment decisions for advanced prostate cancer, in part by helping doctors predict how individual patients will respond to therapy based on the biology of their tumors.

The model is described this week in the online early edition of theĀ Proceedings of the National Academy of Sciences. Jain conducted the work with co-authors Steven Clinton, professor, and Arvinder Bhinder, assistant professor-clinical, in Ohio State’s division of medical oncology, and Avner Friedman, a Distinguished University Professor at Ohio State.

Though the model’s outcomes remain theoretical at this point, the researchers have developed enough of a system to show that their incorporation of some personalized data — details about a patient’s tumor cell characteristics in particular — would give doctors more than they currently have to work with in making decisions about this stage of treatment.

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