Richard Schwab, MD
Dr. Schwab is an Associate Professor of Medicine and the Moores Cancer Center Biorepository co-Director at UC San Diego. He is board certified in Hematology and Medical Oncology. His research is focused on biomarkers to diagnose and refine the treatment of cancer. His current projects include identification of clinically significant genetic changes in breast cancer and development of anti-progesterones to treat early stage breast cancer.
Using next generation sequencing and unique tumor specimens collected by the cancer center Biorepository, he is working to find novel DNA and RNA changes with prognostic or treatment predictive utility.
Additionally Dr. Schwab has opened an investigator IND of the anti-progesterone mifepristone. Using a biomarker based approach he hopes to revive and accelerate the development of anti-progesterone therapy for breast cancer.
In support of these and other biomarker studies Dr. Schwab co-directs a biorepository to prospectively collect de-identified blood, urine and tumor specimens. This resource has a series of key features to maximize its future utility; (1) specimens are associated with detailed clinical data that is regularly updated, (2) samples are stored as small volume aliquots at –80 degrees Celsius to prevent freeze/thaw damage and (3) subjects are consented for germ line DNA sequencing.